SCHEMBL29326369

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27378157	0.88	TRPC5 (0.36)	TRPC5MAPTALDH1A1KMT2AHTT
	SCHEMBL29326371	0.83	MAPK13 (0.40)	TRPC5HCAR1GSK3AGSK3BCYP1A1
	SCHEMBL29326238	0.78	CYP1A1 (0.48)	GSK3AGSK3BCYP1A1CYP1B1ALDH1A1
	SCHEMBL29326380	0.77	KDM4E (0.40)	HCAR1GSK3AGSK3BCYP1A1CYP1B1
	SCHEMBL29326196	0.73	CYP1A1 (0.44)	HCAR1GSK3AGSK3BCYP1A1CYP1B1
	SCHEMBL29326162	0.72	CYP1A1 (0.53)	GSK3AGSK3BCYP1A1CYP1B1ALDH1A1
	SCHEMBL29326391	0.72	KDM4E (0.45)	HCAR1CYP1A1CYP1B1ALDH1A1HTT
	SCHEMBL27378158	0.72	MAPK13 (0.38)	TRPC5ALDH1A1KMT2AKDM4EMAPK13
	SCHEMBL29326382	0.70	TDP1 (0.43)	CYP1A1CYP1B1MEN1KMT2AHTT
	SCHEMBL29326395	0.70	TDP1 (0.43)	CYP1A1CYP1B1HTTITGA4ITGB7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.