Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27378158 | 0.88 | MAPK13 (0.38) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL29326369 | 0.83 | TRPC5 (0.38) | MAPK13MAPK12MAPK11MAPK14CYP1A1 | |
| SCHEMBL29326196 | 0.78 | CYP1A1 (0.44) | CYP1A1CYP1B1HCAR1KDM4EGAA | |
| SCHEMBL29326162 | 0.77 | CYP1A1 (0.53) | CYP1A1CYP1B1KDM4EGAATP53 | |
| SCHEMBL29326395 | 0.75 | TDP1 (0.43) | MAPK13MAPK12MAPK11MAPK14CYP1A1 | |
| SCHEMBL29326382 | 0.75 | TDP1 (0.43) | MAPK13MAPK12MAPK11MAPK14CYP1A1 | |
| SCHEMBL29326183 | 0.74 | ERCC5 (0.43) | CYP1A1CYP1B1HCAR1KDM4EGAA | |
| SCHEMBL29326238 | 0.73 | CYP1A1 (0.48) | CYP1A1CYP1B1KDM4EGAATP53 | |
| SCHEMBL29326391 | 0.72 | KDM4E (0.45) | CYP1A1CYP1B1HCAR1KDM4EGAA | |
| SCHEMBL29326380 | 0.72 | KDM4E (0.40) | CYP1A1CYP1B1HCAR1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | MAPK13 2989/4885MAPK12 3296/4885MAPK11 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.