Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324714 | 0.87 | CYP2D6 (0.42) | ITGB3ITGA2BCYP1A2CYP2D6ALOX15 | |
| SCHEMBL29326427 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BCYP1A2CYP2D6ALOX15 | |
| SCHEMBL29326374 | 0.81 | ALOX15 (0.45) | CYP1A2CYP2D6ALOX15KDM1A | |
| SCHEMBL29324715 | 0.81 | LMNA (0.39) | CYP1A2CYP2D6ALOX15SMN1; SMN2 | |
| SCHEMBL29324697 | 0.80 | CYP1A2 (0.46) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL13218331 | 0.80 | GLA (0.47) | CYP1A2CYP2D6GLASMN1; SMN2MAPK1 | |
| SCHEMBL29326323 | 0.79 | CYP2D6 (0.39) | CYP1A2CYP2D6ALOX15OPRD1 | |
| SCHEMBL29324706 | 0.79 | CYP2D6 (0.37) | ITGB3ITGA2BCYP1A2CYP2D6ALOX15 | |
| SCHEMBL29327479 | 0.78 | ALOX15 (0.45) | CYP1A2CYP2D6ALOX15 | |
| SCHEMBL29326353 | 0.78 | CYP1A2 (0.45) | CYP1A2CYP2D6ALOX15OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | BCL2, BCL2L2, BCL2L1 | ITGB3 3806/4885ITGA2B 2931/4885CYP1A2 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.