Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326555 | 0.93 | ERCC5 (0.36) | ERCC5FEN1PIK3CAADRA1BALDH1A1 | |
| SCHEMBL27192121 | 0.89 | MAPK14 (0.33) | ERCC5FEN1PIK3CAMCHR1PIK3C3 | |
| SCHEMBL30701990 | 0.89 | MAPK14 (0.33) | ERCC5FEN1PIK3CAMCHR1PIK3C3 | |
| SCHEMBL29326527 | 0.86 | HCAR1 (0.40) | ERCC5FEN1PIK3CAADRA1BALDH1A1 | |
| SCHEMBL27378918 | 0.84 | RPS6KA3 (0.35) | ERCC5FEN1PIK3CAMCHR1PIK3C3 | |
| SCHEMBL27381086 | 0.82 | ERCC5 (0.34) | ERCC5FEN1PIK3CAADRA1BHTT | |
| SCHEMBL29326530 | 0.82 | ERCC5 (0.42) | ERCC5FEN1BTKJAK2HTT | |
| SCHEMBL29326559 | 0.80 | PIK3C3 (0.44) | ERCC5FEN1ADRA1BALDH1A1HTT | |
| SCHEMBL29326549 | 0.79 | HSD17B10 (0.38) | ERCC5FEN1BTKJAK2ADRA1B | |
| SCHEMBL30702053 | 0.78 | CYP17A1 (0.39) | ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | ERCC5 2042/4885FEN1 1012/4885BTK 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.