Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27378922 | 0.90 | PIK3C3 (0.40) | PIK3C3ALDH1A1POLBMCHR1ERCC5 | |
| SCHEMBL29326555 | 0.84 | ERCC5 (0.36) | PIK3C3ALDH1A1MCHR1ERCC5FEN1 | |
| SCHEMBL27191808 | 0.83 | MCHR1 (0.41) | PIK3C3MAPTALDH1A1MCHR1MEN1 | |
| SCHEMBL29326522 | 0.81 | TNKS2 (0.46) | PIK3C3HSD17B10ALOX15MAPTALDH1A1 | |
| SCHEMBL29326527 | 0.81 | HCAR1 (0.40) | HSD17B10ALDH1A1ERCC5FEN1ADRA1B | |
| SCHEMBL29326494 | 0.80 | ERCC5 (0.35) | PIK3C3HSD17B10ALDH1A1PKMMCHR1 | |
| SCHEMBL27191946 | 0.79 | HTR7 (0.40) | HSD17B10MAPTERCC5FEN1HTR1A | |
| SCHEMBL30702007 | 0.79 | HTR7 (0.40) | HSD17B10MAPTERCC5FEN1HTR1A | |
| SCHEMBL29326162 | 0.79 | CYP1A1 (0.53) | ALDH1A1POLBERCC5FEN1TDP1 | |
| SCHEMBL30702065 | 0.78 | ATR (0.35) | MCHR1ERCC5FEN1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | PIK3C3 4042/4885HSD17B10 433/4885ALOX15 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.