Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 9/20 | 0.71 |
| ▸ | TNF | P01375 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326569 | 0.88 | IL1B (0.53) | IL1BTNFNLRP3CRHR1 | |
| SCHEMBL29326772 | 0.87 | IL1B (0.65) | IL1BTNFNLRP3PIM1PIM2 | |
| SCHEMBL29326368 | 0.85 | IL1B (0.69) | IL1BTNFNLRP3 | |
| SCHEMBL26132225 | 0.85 | IL1B (0.69) | IL1BTNFNLRP3 | |
| SCHEMBL30054549 | 0.85 | IL1B (0.69) | IL1BTNFNLRP3 | |
| SCHEMBL24695700 | 0.85 | IL1B (0.69) | IL1BTNFNLRP3 | |
| SCHEMBL29326389 | 0.85 | IL1B (0.69) | IL1BTNFNLRP3 | |
| SCHEMBL26434285 | 0.83 | IL1B (0.52) | IL1BTNFNLRP3 | |
| SCHEMBL29326531 | 0.83 | IL1B (0.52) | IL1BTNFNLRP3 | |
| SCHEMBL22655097 | 0.83 | IL1B (1.00) | IL1BTNFNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | IL1B 11/4885TNF 67/4885NLRP3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.