SCHEMBL29326637

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26434544	0.90	IL1B (0.47)	IL1BTNFNLRP3SMN1; SMN2
	SCHEMBL29326633	0.89	NLRP3 (0.41)	IL1BTNFNLRP3CDK2CDK9
	SCHEMBL29326643	0.86	NLRP3 (0.47)	IL1BTNFNLRP3CDK2CDK9
	SCHEMBL30375405	0.85	IL1B (0.52)	IL1BTNFNLRP3TRPV1
	SCHEMBL26092873	0.85	IL1B (0.52)	IL1BTNFNLRP3TRPV1
	SCHEMBL30684741	0.85	IL1B (0.52)	IL1BTNFNLRP3TRPV1
	SCHEMBL27182193	0.85	IL1B (0.52)	IL1BTNFNLRP3TRPV1
	Hydrochloric Acid SCHEMBL29975485	0.84	IL1B (0.52)	IL1BTNFNLRP3TRPV1
	SCHEMBL29326630	0.82	NLRP3 (0.52)	IL1BTNFNLRP3
	SCHEMBL29326647	0.82	IL1B (0.51)	IL1BTNFNLRP3PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.