Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31056876 | 0.99 | KDM4E (0.43) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL29326268 | 0.87 | CA12 (0.43) | KDM4EALDH1A1GAASMN1; SMN2HTR6 | |
| Hydrochloric Acid SCHEMBL31056912 | 0.86 | CA12 (0.43) | KDM4EALDH1A1GAASMN1; SMN2HTR6 | |
| SCHEMBL29328207 | 0.80 | MEN1 (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL31056797 | 0.79 | MEN1 (0.44) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL29321284 | 0.78 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL24792464 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL30280751 | 0.72 | ALDH1A1 (0.55) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL26800328 | 0.71 | KDM4E (0.54) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL12466618 | 0.70 | QDPR (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |