Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379357 | 0.88 | METAP2 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326517 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326426 | 0.78 | HSD17B10 (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2HIF1A | |
| SCHEMBL27378765 | 0.74 | TNKS2 (0.43) | KDM4EALDH1A1HPGDGAATP53 | |
| SCHEMBL27192042 | 0.73 | HSD17B10 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2TP53 | |
| SCHEMBL27379779 | 0.73 | METAP2 (0.44) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL31681236 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2CA9HSD17B10 | |
| SCHEMBL27380985 | 0.71 | NPBWR1 (0.36) | KDM4EALDH1A1HPGDSMN1; SMN2HIF1A | |
| SCHEMBL27381490 | 0.71 | METAP2 (0.38) | KDM4EALDH1A1CA12CA2CA9 | |
| SCHEMBL27191886 | 0.71 | HSD17B10 (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | KDM4E 3744/4885ALDH1A1 3259/4885HPGD 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.