Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BCAT1 | P54687 | 12/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 5/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191737 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL30701974 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL29326342 | 0.86 | NPEPPS (0.39) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL30702073 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL27191901 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL27380568 | 0.79 | CYP11B1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL27192321 | 0.79 | HSD17B10 (0.43) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL30701994 | 0.79 | HSD17B10 (0.43) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL29326760 | 0.78 | HSD17B10 (0.48) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL29326253 | 0.77 | NPEPPS (0.42) | ALDH1A1KDM4EHPGDHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | ALDH1A1 3259/4885KDM4E 3744/4885HPGD 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.