Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 18/20 | 0.38 |
| ▸ | CCND1 | P24385 | 18/20 | 0.38 |
| ▸ | CCND3 | P30281 | 18/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 18/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326748 | 0.88 | CDK4 (0.37) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL29326455 | 0.87 | CDK4 (0.40) | CDK4CCND1CCND3CDK6IL1B | |
| SCHEMBL29975874 | 0.87 | CDK4 (0.40) | CDK4CCND1CCND3CDK6IL1B | |
| SCHEMBL29326752 | 0.85 | KCNH2 (0.44) | IL1B | |
| SCHEMBL29326732 | 0.85 | NLRP3 (0.48) | CDK4CCND1CCND3CDK6IL1B | |
| SCHEMBL29326740 | 0.83 | IL1B (0.40) | CDK4CCND1CCND3CDK6IL1B | |
| SCHEMBL29326626 | 0.78 | NLRP3 (0.39) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL29326535 | 0.76 | CDK4 (0.38) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL29326775 | 0.74 | IL1B (0.61) | IL1B | |
| SCHEMBL29326094 | 0.73 | CDK4 (0.35) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | CDK4 2774/4885CCND1 4369/4885CCND3 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.