Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599200 | 1.00 | TDP1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL8024010 | 1.00 | TDP1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL8024004 | 1.00 | TDP1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9059526 | 0.87 | TP53 (0.47) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5250951 | 0.86 | CA2 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5907622 | 0.84 | GPR84 (0.57) | GPR84FFAR1SLC1A2SLC1A1GRIK1 | |
| SCHEMBL5031485 | 0.84 | TDP1 (0.60) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL14110749 | 0.84 | TDP1 (0.60) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9431401 | 0.82 | GPR84 (0.61) | GPR84FFAR1GRIK1GRIK2ACE2 | |
| Undecane SCHEMBL20589952 | 0.82 | GPR84 (0.55) | GPR84FFAR1CA2MAPK1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| EP-0859858-B1 | METHODS FOR ISOLATING POLYHYDROXYALKANOATES FROM PLANTS | METABOLIX INC (US) | 2007-09-19 | — | — | EP | disclosed |
| US-20060046286-A1 | Method for preparing optically active beta-butyrolactones | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |
| US-6709848-B1 | DERIVATIZATION OF POLYHYDROXYALKANOATE FROM A BIOMASS DERIVED FROM A TRANSGENIC PLANT, FOLLOWED BY SEPARATION | METABOLIX, INC. | 2004-03-23 | — | — | US | disclosed |
| US-20020127609-A1 | Screening for enzyme stereoselectivity utilizing mass spectrometry | MAXYGEN, INC. | 2002-09-12 | — | — | US | disclosed |
| WO-2002068931-A2 | SCREENING FOR ENZYME STEREOSELECTIVITY UTILIZING MASS SPECTROMETRY | MAXYGEN, INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-0859858-A1 | METHODS FOR ISOLATING POLYHYDROXYALKANOATES FROM PLANTS | METABOLIX, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997015681-A9 | METHODS FOR ISOLATING POLYHYDROXYALKANOATES FROM PLANTS | — | 1997-07-17 | — | — | WO | disclosed |
| WO-1997015681-A1 | METHODS FOR ISOLATING POLYHYDROXYALKANOATES FROM PLANTS | METABOLIX, INC. (US) | 1997-05-01 | — | — | WO | disclosed |
| WO-1981002894-A1 | POLYMER COMPOSITIONS AND MANUFACTURE | TEXTRON INC (US) | 1981-10-15 | — | — | WO | disclosed |