SCHEMBL2932679

SCHEMBL2932679

O=C1NC(=O)c2c(I)cccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.52
TDP2 O95551 1/20 0.52
PARP1 P09874 5/20 0.48
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 3/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CASP3 P42574 5/20 0.45
CASP7 P55210 2/20 0.45
CASP2 P42575 1/20 0.45
CASP6 P55212 1/20 0.45
CASP8 Q14790 1/20 0.45
POLB P06746 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
RGS12 O14924 1/20 0.40
USP2 O75604 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16754925 0.81 GSK3B (0.62) GSK3BTDP2PARP1KDM4EALDH1A1
SCHEMBL28935123 0.77 PARP1 (0.63) GSK3BTDP2PARP1KDM4EALDH1A1
SCHEMBL1499914 0.76 GSK3B (0.54) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL14763938 0.76 GSK3B (0.54) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL9561195 0.76 GSK3B (0.54) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL7795435 0.76 TDP2 (0.53) GSK3BTDP2L3MBTL1PDGFRAFER
SCHEMBL5165149 0.74 GSK3B (0.52) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL1080129 0.74 GSK3B (0.52) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL112742 0.74 GSK3B (0.52) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL7943830 0.74 PARP1 (0.44) GSK3BTDP2PARP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3941995-A1 DISUBSTITUTED FLUOROARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI S.p.A. (IT) 2022-01-26 EP claimed
WO-2020194147-A1 DISUBSTITUTED FLUOROARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI S.P.A. (IT) 2020-10-01 WO claimed
CN-108117645-B Method for preparing polyaryl imide and production device thereof 北京鼎益新材科技有限公司 2020-08-14 CN claimed
CN-109134392-A N2-alkenyl benzotriazole derivative and synthetic method thereof 周口师范学院 2019-01-04 CN claimed
CN-108473486-A Disubstituted miscellaneous diazole compounds of two aryloxy group benzo 埃尼股份公司 2018-08-31 CN claimed
CN-108117645-A The poly- fragrant acid imide manufacturing method of one kind and its process units 梅雪 2018-06-05 CN claimed
CN-108117505-A A kind of preparation method for synthesizing diphenyl ether imidodicarbonic diamide 杜庶铭 2018-06-05 CN claimed
EP-3197890-A1 DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI S.p.A. (IT) 2017-08-02 EP claimed
WO-2016046319-A1 DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI S.P.A. (IT) 2016-03-31 WO claimed
US-4181530-A ELECTRON ATTRACTING PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-01-01 US claimed
CN-119954628-A Process for the preparation of quinones 中国石油化工股份有限公司 2025-05-09 CN disclosed
EP-3590982-B1 METHOD FOR PRODUCING GRAFT POLYMER UNIV KYOTO (JP) 2025-04-30 EP disclosed
US-11407849-B2 Method for manufacturing graft polymer, graft polymer, and initiator of graft polymer KYOTO UNIVERSITY LTD. 2022-08-09 US disclosed
EP-3737678-B1 PROCESS FOR THE PREPARATION OF DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI SPA (IT) 2022-06-29 EP disclosed
EP-3941995-A1 DISUBSTITUTED FLUOROARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI S.p.A. (IT) 2022-01-26 EP disclosed
EP-0816364-B1 Reagents for lysergic acid diethylamide immunoassay HOFFMANN LA ROCHE (CH) 2004-01-02 EP disclosed
US-6476199-B1 Reagents for lysergic acid diethylamide immunoassay ROCHE DIAGNOSTICS CORPORATION 2002-11-05 US disclosed
US-6063908-A STABLE HAPTEN DERIVATIVES THAT ARE USEFUL FOR THE PREPARATION OF ANTIGENS, ANTIBODIES AND REAGENTS USED IN DETECTION OF DRUG ABUSE ROCHE DIAGNOSTICS CORPORATION (US) 2000-05-16 US disclosed
EP-0816364-A1 Reagents for lysergic acid diethylamide immunoassay F. HOFFMANN-LA ROCHE AG (CH) 1998-01-07 EP disclosed
US-4181530-A ELECTRON ATTRACTING PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-01-01 US disclosed