Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 16/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326834 | 0.89 | IL1B (0.42) | SYKAURKBKCNH2 | |
| SCHEMBL29326482 | 0.87 | NLRP3 (0.51) | KCNH2NLRP3 | |
| SCHEMBL26434277 | 0.87 | NLRP3 (0.51) | KCNH2NLRP3 | |
| SCHEMBL29975511 | 0.86 | NLRP3 (0.56) | SYKKCNH2NLRP3 | |
| SCHEMBL29326805 | 0.86 | NLRP3 (0.56) | SYKKCNH2NLRP3 | |
| Hydrochloric Acid SCHEMBL29975257 | 0.85 | NLRP3 (0.55) | SYKKCNH2NLRP3 | |
| Hydrochloric Acid SCHEMBL27182168 | 0.85 | NLRP3 (0.55) | SYKKCNH2NLRP3 | |
| SCHEMBL29326833 | 0.84 | IL1B (0.47) | SYKKCNH2NLRP3 | |
| SCHEMBL29326175 | 0.79 | SYK (0.40) | SYKKCNH2NLRP3 | |
| SCHEMBL31130797 | 0.78 | SYK (0.49) | SYKAURKBNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | SYK 813/4885AURKB 4230/4885KCNH2 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.