Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29327531 | 0.92 | ALDH1A1 (0.60) | PTGESALDH1A1GAANPSR1SMN1; SMN2 | |
| SCHEMBL14970840 | 0.78 | TP53 (0.71) | PTGESALDH1A1SMN1; SMN2TP53THRB | |
| SCHEMBL18559238 | 0.74 | ALDH1A1 (1.00) | ALDH1A1GAANPSR1SMN1; SMN2TP53 | |
| SCHEMBL13739459 | 0.74 | ALDH1A1 (0.62) | ALDH1A1GAANPSR1MAPTTSHR | |
| SCHEMBL13739721 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GAANPSR1MAPTTSHR | |
| SCHEMBL20682668 | 0.74 | GAA (0.71) | ALDH1A1GAANPSR1TP53USP2 | |
| SCHEMBL18559152 | 0.74 | GAA (0.84) | ALDH1A1GAASMN1; SMN2TP53MAPT | |
| SCHEMBL18559342 | 0.74 | ALDH1A1 (1.00) | ALDH1A1GAANPSR1SMN1; SMN2THRB | |
| SCHEMBL15986095 | 0.73 | LMNA (0.67) | ALDH1A1GAANPSR1SMN1; SMN2TP53 | |
| SCHEMBL15983718 | 0.72 | ALDH1A1 (0.82) | PTGESALDH1A1NPSR1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239786-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER | YALE UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239786-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER | BRCA1, RAD51, PARP3 | PTGES 1447/4885ALDH1A1 343/4885GAA 3007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.