Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | PTGES | O14684 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | SLC27A1 | Q6PCB7 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15983404 | 0.81 | LMNA (0.82) | TP53SMN1; SMN2PTGESALDH1A1MAPT | |
| SCHEMBL4212019 | 0.78 | TSHR (0.88) | SMN1; SMN2ALDH1A1MAPTALOX15TSHR | |
| SCHEMBL4206912 | 0.78 | TSHR (0.88) | SMN1; SMN2SLC27A1ALDH1A1MAPTALOX15 | |
| SCHEMBL14970841 | 0.78 | THRB (0.68) | SMN1; SMN2PTGESTHRBALDH1A1MAPT | |
| SCHEMBL15983718 | 0.78 | ALDH1A1 (0.82) | SMN1; SMN2PTGESSLC27A1ALDH1A1USP2 | |
| SCHEMBL29327093 | 0.78 | PTGES (0.60) | TP53SMN1; SMN2PTGESTHRBALDH1A1 | |
| SCHEMBL18559345 | 0.78 | SMN1; SMN2 (1.00) | TP53SMN1; SMN2THRBALDH1A1MAPT | |
| SCHEMBL15983241 | 0.77 | NPSR1 (0.70) | TP53SMN1; SMN2PTGESALDH1A1USP2 | |
| SCHEMBL18559154 | 0.76 | SMN1; SMN2 (0.85) | TP53SMN1; SMN2THRBSLC27A1ALDH1A1 | |
| SCHEMBL18559361 | 0.76 | ALDH1A1 (0.72) | TP53SMN1; SMN2THRBSLC27A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275224-A1 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275224-A1 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-09-18 | — | — | US | disclosed |
| WO-2013074059-A2 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275224-A1 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | CDA, DCTD, ADA | TP53 1987/4885SMN1; SMN2 2561/4885PTGES 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.