Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 11/20 | 0.51 |
| ▸ | MC3R | P41968 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | MC5R | P33032 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046351 | 0.83 | FAAH (0.53) | MC4RMC5RPRCP | |
| SCHEMBL29327370 | 0.83 | FAAH (0.53) | MC4RMC5RPRCP | |
| SCHEMBL29327363 | 0.82 | MC4R (0.61) | MC4RMC3RKCNH2MC5R | |
| SCHEMBL29327361 | 0.82 | MC4R (0.61) | MC4RMC3RKCNH2MC5R | |
| SCHEMBL29327407 | 0.82 | MC4R (0.52) | MC4RMC3RKCNH2MC5R | |
| SCHEMBL29327414 | 0.82 | MC4R (0.54) | MC4RMC3RKCNH2MC5RALDH1A1 | |
| SCHEMBL29327416 | 0.82 | MC4R (0.54) | MC4RMC3RKCNH2MC5RALDH1A1 | |
| SCHEMBL29327366 | 0.78 | MC4R (0.53) | MC4RKCNH2MC5RPRCP | |
| SCHEMBL29327368 | 0.78 | MC4R (0.53) | MC4RKCNH2MC5RPRCP | |
| SCHEMBL29327118 | 0.76 | MC4R (0.60) | MC4RMC3RKCNH2MC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | AQP3, SLC6A7, ABCG2 | MC4R 2367/4885MC3R 1834/4885KCNH2 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.