Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603589 | 0.85 | P2RX3 (0.49) | P2RX3P2RX2ARGAAIMPDH2 | |
| SCHEMBL2473900 | 0.80 | GAA (0.45) | GAANPC1IMPDH2IMPDH1KDM4E | |
| SCHEMBL16918776 | 0.79 | P2RX3 (0.42) | P2RX3P2RX2ARGAAIMPDH2 | |
| SCHEMBL29328240 | 0.79 | P2RX3 (0.42) | P2RX3P2RX2ARGAAIMPDH2 | |
| SCHEMBL14039591 | 0.77 | NPC1 (0.52) | P2RX3P2RX2GAANPC1KDM4E | |
| SCHEMBL27376906 | 0.77 | SRC (0.45) | ARIDH1GAANPC1KDM4E | |
| SCHEMBL13748193 | 0.77 | P2RX3 (0.58) | P2RX3P2RX2ARGAAIMPDH2 | |
| SCHEMBL11153594 | 0.75 | NPC1 (0.60) | GAANPC1IMPDH2IMPDH1KDM4E | |
| SCHEMBL2153709 | 0.74 | GABRA1 (0.37) | P2RX3P2RX2ARIMPDH2IMPDH1 | |
| SCHEMBL5874040 | 0.74 | P2RX3 (0.46) | P2RX3P2RX2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | P2RX3 4454/4885P2RX2 3777/4885AR 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.