Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076845 | 0.78 | KDM4E (0.47) | HTTMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL30988614 | 0.78 | KDM4E (0.47) | HTTMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL29328366 | 0.77 | HTT (0.44) | HTTMAPK1TP53KDM4EALDH1A1 | |
| SCHEMBL25076838 | 0.77 | MEN1 (0.48) | HTTMAPK1TP53KDM4EALDH1A1 | |
| SCHEMBL13741356 | 0.77 | ALDH1A1 (0.48) | HTTMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL3529098 | 0.75 | ALDH1A1 (0.47) | HTTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17782257 | 0.75 | ALDH1A1 (0.47) | HTTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9409583 | 0.75 | HTT (0.57) | HTTMAPK1TP53KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1652940 | 0.74 | ALDH1A1 (0.46) | HTTKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL17782206 | 0.74 | ALDH1A1 (0.46) | HTTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |