Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988614 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL31056427 | 0.82 | CTSL (0.38) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL29325641 | 0.82 | CTSL (0.38) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL15203702 | 0.81 | TSHR (0.41) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13741356 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL29328473 | 0.79 | MEN1 (0.42) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL29320338 | 0.79 | CA12 (0.48) | GAAMEN1KMT2ASMN1; SMN2CA1 | |
| SCHEMBL3529098 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL17782257 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL29324957 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595270-B2 | Benzo nitrogen-containing heteroaromatic ring derivative and use thereof in medicine | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2026-04-07 | — | — | US | disclosed |
| US-20260035385-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2026-02-05 | — | — | US | disclosed |
| EP-4649998-A2 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2025-11-19 | — | — | EP | disclosed |
| US-20240383917-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| US-20240360103-A1 | COMPLEMENT INHIBITION | SIXTH STREET LENDING PARTNERS | 2024-10-31 | — | — | US | disclosed |
| EP-4389742-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-06-26 | — | — | EP | disclosed |
| CN-118043314-A | Benzazepine heteroaromatic ring derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-4362933-A1 | COMPLEMENT INHIBITION | Apellis Pharmaceuticals, Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023020566-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2023-02-23 | — | — | WO | disclosed |
| WO-2023020566-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2023-02-23 | — | — | WO | disclosed |
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035385-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | CYP2F1, CFH, CYP4F11 | KDM4E 1391/4885ALDH1A1 2219/4885HSD17B10 427/4885 |
| US-20240383917-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | C9, CFB, CYP4F11 | KDM4E 3513/4885ALDH1A1 2325/4885HSD17B10 436/4885 |
| US-12595270-B2 | Benzo nitrogen-containing heteroaromatic ring derivative and use thereof in medicine | CYP2F1, CYP4F11, CFH | KDM4E 1401/4885ALDH1A1 2025/4885HSD17B10 414/4885 |
| US-20240360103-A1 | COMPLEMENT INHIBITION | C5, C9, C1QBP | KDM4E 1096/4885ALDH1A1 2375/4885HSD17B10 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.