Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26067851 | 0.95 | FGFR1 (0.38) | FGFR1FGFR4KMOCYP1A2HTR2A | |
| SCHEMBL29328565 | 0.81 | KMO (0.56) | KMOCYP1A2P2RX7DAORECQL | |
| SCHEMBL29411862 | 0.81 | FGFR1 (0.42) | FGFR1FGFR4KMOCYP1A2HTR2A | |
| SCHEMBL3632921 | 0.81 | FGFR1 (0.42) | FGFR1FGFR4KMOCYP1A2HTR2A | |
| SCHEMBL8803921 | 0.78 | SLC9A1 (0.40) | FGFR1FGFR4KMOCYP1A2HTR2A | |
| SCHEMBL29328557 | 0.78 | KMO (0.63) | FGFR1FGFR4KMO | |
| SCHEMBL26055397 | 0.77 | KMO (0.39) | FGFR1FGFR4KMOCYP1A2HTR2A | |
| SCHEMBL29972506 | 0.76 | KMO (0.41) | FGFR1FGFR4KMOCYP1A2HTR2A | |
| SCHEMBL19249519 | 0.72 | FGFR1 (0.39) | FGFR1FGFR4KMOCYP1A2HTR2A | |
| SCHEMBL29989046 | 0.72 | HASPIN (0.49) | FGFR1FGFR4CYP1A2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234609-B1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | POLYPLUS TRANSFECTION (FR) | 2024-07-17 | — | — | EP | disclosed |