Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 7/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965232 | 0.82 | KMO (0.82) | KMOPDE4BPDE4DPTGIRS1PR1 | |
| SCHEMBL29972445 | 0.81 | KMO (0.59) | KMONPSR1KDM4EHSD17B10FGFR1 | |
| SCHEMBL22965255 | 0.81 | KDM4E (0.44) | KMOPDE4BPDE4DKDM4ETSHR | |
| SCHEMBL26055397 | 0.78 | KMO (0.39) | KMOFGFR1FGFR4 | |
| SCHEMBL29972506 | 0.78 | KMO (0.41) | KMOFGFR1FGFR4 | |
| SCHEMBL29328869 | 0.78 | FGFR1 (0.39) | KMOFGFR1FGFR4 | |
| SCHEMBL8803921 | 0.77 | SLC9A1 (0.40) | KMOFGFR1FGFR4 | |
| SCHEMBL26067851 | 0.77 | FGFR1 (0.38) | KMOFGFR1FGFR4 | |
| SCHEMBL13978502 | 0.74 | KMO (0.43) | KMOKDM4ETSHRHSD17B10FGFR1 | |
| SCHEMBL7632528 | 0.73 | NPSR1 (0.43) | KMONPSR1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234609-B1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | POLYPLUS TRANSFECTION (FR) | 2024-07-17 | — | — | EP | disclosed |