SCHEMBL29328904

SCHEMBL29328904

CCOC(=O)C(/C(=C/C(=N)C(F)(F)F)Nc1ccc(C(F)(F)F)cc1)c1ncc(Cl)cc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
RECQL P46063 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 2/20 0.36
TRPV1 Q8NER1 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
PSMB5 P28074 1/20 0.36
IDH1 O75874 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CNR1 P21554 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25711596 0.87 MAPT (0.45) CYP1A2CYP3A4CYP2C19RECQLMEN1
SCHEMBL25711613 0.80 MAPT (0.45) CYP1A2CYP3A4CYP2C19RECQLMEN1
SCHEMBL25711749 0.77 MEN1 (0.36) CYP1A2CYP3A4CYP2C19RECQLMEN1
SCHEMBL896613 0.74 S1PR3 (0.53) CYP1A2CYP3A4CYP2C19RECQLMEN1
SCHEMBL29328870 0.72 ALDH1A1 (0.37) LMNASMN1; SMN2KDM4EALDH1A1TRPV1
SCHEMBL29328879 0.71 CYP3A4 (0.37) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL29329154 0.69 CYP1A2 (0.43) CYP1A2CYP3A4CYP2C19RECQLMEN1
SCHEMBL29328896 0.68 MAPT (0.52) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL29329158 0.67 CYP1A2 (0.42) CYP1A2CYP3A4CYP2C19RECQLMEN1
SCHEMBL5211782 0.66 KMT2A (0.82) CYP1A2CYP3A4CYP2C19RECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149676-A1 HERBICIDAL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-07-18 WO disclosed