SCHEMBL29328920

SCHEMBL29328920

O=C1CCC(=O)C12CCCC2

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.33
TRIM24 O15164 2/20 0.32
TRIM33 Q9UPN9 2/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2015392 0.97 ALDH1A1 (0.35) CRBNTRIM24TRIM33ESR1ESR2
SCHEMBL2015391 0.97 ALDH1A1 (0.35) CRBNTRIM24TRIM33ESR1ESR2
SCHEMBL6757693 0.88 CRBN (0.36) CRBNTRIM24TRIM33ESR1ESR2
SCHEMBL6757690 0.88 CRBN (0.36) CRBNTRIM24TRIM33ESR1ESR2
SCHEMBL11866693 0.88 CRBN (0.36) CRBN
SCHEMBL1903325 0.87 CRBN (0.33) CRBNTRIM24TRIM33ALDH1A1
SCHEMBL3646429 0.78 MEN1 (0.48) TRIM24TRIM33ALDH1A1
SCHEMBL2982384 0.78 ALDH1A1 (0.33) ESR1ESR2ALDH1A1
SCHEMBL2988042 0.78 ALDH1A1 (0.33) ESR1ESR2ALDH1A1
SCHEMBL6614335 0.77 OPRM1 (0.35) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151112-A1 PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR 주식회사 티움바이오 2024-07-18 WO disclosed
CN-117800944-A Pyridine amide derivative, pharmaceutical composition containing same and medical application of pharmaceutical composition 苏州阿尔脉生物科技有限公司 2024-04-02 CN disclosed