Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757693 | 1.00 | CRBN (0.36) | CRBNALDH1A1TRIM24TRIM33L3MBTL1 | |
| SCHEMBL11866693 | 0.94 | CRBN (0.36) | CRBN | |
| SCHEMBL2015392 | 0.91 | ALDH1A1 (0.35) | CRBNALDH1A1TRIM24TRIM33L3MBTL1 | |
| SCHEMBL2015391 | 0.91 | ALDH1A1 (0.35) | CRBNALDH1A1TRIM24TRIM33L3MBTL1 | |
| SCHEMBL29328920 | 0.88 | CRBN (0.33) | CRBNALDH1A1TRIM24TRIM33ESR1 | |
| SCHEMBL1903325 | 0.88 | CRBN (0.33) | CRBNALDH1A1TRIM24TRIM33 | |
| SCHEMBL2982384 | 0.79 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL2988042 | 0.79 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL1373550 | 0.76 | OPRM1 (0.38) | CRBN | |
| SCHEMBL15543801 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716865-B1 | SUBSTITUTED AT THE 2 POSITION; A SULFAMATE BOUND VIA OXYGEN TO THE PHENYL PART OF THE RING STRUCTURE; SULFAMOYLATION; STEROID SULFATASE INHIBITOR, ACNE | NOVARTIS AG (CH) | 2004-04-06 | — | — | US | disclosed |