Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24576746 | 0.80 | TDP1 (0.54) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29329031 | 0.78 | POLB (0.46) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29329021 | 0.77 | KMT2A (0.50) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29329014 | 0.74 | RAB9A (0.45) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL20305864 | 0.74 | TDP1 (0.54) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL20201218 | 0.74 | TDP1 (0.47) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL28833854 | 0.73 | TDP1 (0.50) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL26381487 | 0.73 | RAB9A (0.49) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL14768871 | 0.73 | TDP1 (0.66) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29329029 | 0.72 | L3MBTL1 (0.52) | L3MBTL1TDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |