SCHEMBL29329022

SCHEMBL29329022

CCOC(=O)C(c1cccc(C(F)(F)F)n1)c1cc(C(F)(F)F)nn1Cc1ccc(OC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
SLC16A3 O15427 1/20 0.38
SLC16A1 P53985 1/20 0.38
MCTS1 Q9ULC4 1/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
THRB P10828 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
USP2 O75604 1/20 0.37
GLA P06280 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25263130 0.82 MAPT (0.41) MAPTAKR1C3SLC16A3SLC16A1MCTS1
SCHEMBL1056343 0.76 HDAC3 (0.43) AKR1C3AKR1C2SLC16A3SLC16A1MCTS1
SCHEMBL27165198 0.76 MAPT (0.40) MAPTSLC16A3SLC16A1MCTS1PTGDR2
SCHEMBL25225321 0.74 MAPT (0.44) MAPTAKR1C3AKR1C2PTGDR2THRB
SCHEMBL660341 0.73 ASIC1 (0.41) AKR1C3AKR1C2SLC16A3SLC16A1MCTS1
SCHEMBL2688186 0.72 GRN (0.57) MAPTAKR1C3ALDH1A1GAANPSR1
SCHEMBL659074 0.72 EPHX1 (0.40) MAPTAKR1C3AKR1C2
SCHEMBL1197409 0.71 KDM4E (0.52) MAPTKDM4EALDH1A1GAAHPGD
SCHEMBL30999698 0.70 GRIN1 (0.40) MAPTAKR1C3AKR1C2NR1H2NR1H3
SCHEMBL29329040 0.70 GRIN1 (0.40) MAPTAKR1C3AKR1C2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4649076-A1 HERBICIDAL PYRAZOLE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-11-19 EP disclosed
WO-2024149676-A1 HERBICIDAL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-07-18 WO disclosed
WO-2024149676-A1 HERBICIDAL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-07-18 WO disclosed