Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165200 | 0.93 | MAPT (0.44) | MAPTAKR1C3MEN1KMT2AUCHL1 | |
| SCHEMBL29329150 | 0.83 | MAPT (0.45) | MAPTMEN1KMT2AUCHL1PKM | |
| SCHEMBL2686354 | 0.81 | PTGER4 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL287956 | 0.79 | PTGS2 (0.44) | MAPTAKR1C3 | |
| SCHEMBL30859967 | 0.79 | ALDH1A1 (0.46) | MAPTAKR1C3KMT2AUCHL1PKM | |
| SCHEMBL287302 | 0.77 | AKR1C3 (0.41) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1197409 | 0.77 | KDM4E (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2688186 | 0.77 | GRN (0.57) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4070158 | 0.76 | ALDH1A1 (0.47) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5064196 | 0.76 | PTGER4 (0.42) | MAPTHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4649076-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-19 | — | — | EP | disclosed |
| EP-4441041-B1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-4581022-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-07-09 | — | — | EP | disclosed |
| WO-2025098854-A1 | 5-MEMBERED HETEROARYL AND PYRAZOLE HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2025-05-15 | — | — | WO | disclosed |
| US-20250042876-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-06 | — | — | US | disclosed |
| EP-4441041-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-10-09 | — | — | EP | disclosed |
| WO-2024149676-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024149676-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024046890-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023099354-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023099354-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042876-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHX35 | MAPT 3932/4885HDAC3 1783/4885HDAC4 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.