Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328988 | 0.77 | RAB9A (0.42) | MAPTRAB9ASTAT1NPSR1POLB | |
| SCHEMBL29328986 | 0.75 | MAPT (0.40) | MAPTRAB9ASTAT1NPSR1POLB | |
| SCHEMBL21950425 | 0.74 | RAB9A (0.55) | MAPTRAB9ASTAT1NPSR1POLB | |
| SCHEMBL20348533 | 0.74 | TDP1 (0.56) | MAPTRAB9ASTAT1NPSR1POLB | |
| SCHEMBL19884269 | 0.74 | ALDH1A1 (0.43) | MAPTRAB9ASTAT1NPSR1POLB | |
| SCHEMBL25541336 | 0.73 | TDP1 (0.51) | MAPTRAB9ASTAT1NPSR1ALDH1A1 | |
| SCHEMBL29329021 | 0.73 | KMT2A (0.50) | MAPTRAB9ASTAT1NPSR1POLB | |
| SCHEMBL29329014 | 0.73 | RAB9A (0.45) | MAPTRAB9ASTAT1NPSR1POLB | |
| SCHEMBL25713483 | 0.73 | TDP1 (0.64) | MAPTRAB9AALDH1A1HPGDTDP1 | |
| SCHEMBL21572853 | 0.72 | TDP1 (0.58) | MAPTRAB9ASTAT1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |