Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328988 | 0.84 | RAB9A (0.42) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL29329026 | 0.75 | MAPT (0.45) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL29329027 | 0.74 | POLB (0.46) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL19884269 | 0.71 | ALDH1A1 (0.43) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL21950425 | 0.69 | RAB9A (0.55) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL29329029 | 0.69 | L3MBTL1 (0.52) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL29329031 | 0.69 | POLB (0.46) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL24704431 | 0.69 | TDP1 (0.49) | MAPTRAB9AATMSTAT1NPSR1 | |
| SCHEMBL523555 | 0.68 | ALDH1A1 (0.46) | MAPTRAB9APOLBTDP1SLC6A2 | |
| SCHEMBL25541336 | 0.68 | TDP1 (0.51) | MAPTRAB9ASTAT1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |