Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909506 | 0.84 | KCNA5 (0.39) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL22879264 | 0.84 | KCNA5 (0.39) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10232877 | 0.84 | KCNA5 (0.39) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13066097 | 0.84 | KCNA5 (0.37) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL23103016 | 0.75 | KCNA5 (0.33) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL21447274 | 0.75 | ALDH1A1 (0.35) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL22854206 | 0.75 | KCNA5 (0.33) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13024056 | 0.74 | KCNA5 (0.39) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL24827726 | 0.73 | MC4R (0.36) | KCNA5ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL57306 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | KCNA5 2736/4885ALDH1A1 843/4885KMT2A 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.