SCHEMBL29329237

SCHEMBL29329237

COC(=O)CC(=O)Nc1cc(CO)cc(CO)c1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 2/20 0.39
CYP2C19 P33261 1/20 0.39
HPGD P15428 1/20 0.39
CTSL P07711 1/20 0.39
PTPRC P08575 1/20 0.39
PTPN13 Q12923 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19463069 0.82 HDAC8 (0.54) L3MBTL1KMT2AALDH1A1MEN1HTT
SCHEMBL24239916 0.78 CA12 (0.51) L3MBTL1KMT2APOLBALDH1A1MEN1
SCHEMBL17570931 0.77 RECQL (0.47) L3MBTL1KMT2AMEN1PTPRCPTPN13
SCHEMBL2711919 0.76 KMT2A (0.49) L3MBTL1KMT2APOLBALDH1A1MEN1
SCHEMBL13223975 0.76 HSP90AB1 (0.39) L3MBTL1KMT2APOLBALDH1A1MEN1
SCHEMBL29329240 0.76 ALDH1A1 (0.44) L3MBTL1KMT2AALDH1A1MEN1HTT
SCHEMBL21029724 0.75 LMNA (0.54) L3MBTL1KMT2APOLBALDH1A1MEN1
SCHEMBL22987302 0.74 KDM4E (0.38) L3MBTL1KMT2APOLBALDH1A1MEN1
SCHEMBL3142093 0.74 HPGD (0.45) L3MBTL1KMT2APOLBALDH1A1MEN1
SCHEMBL21029725 0.72 MAPT (0.34) L3MBTL1KMT2APOLBALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043833-B2 Targeted compositions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed