Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23588941 | 0.78 | USP2 (0.40) | USP2HSD11B1HDAC2HDAC1TSHR | |
| SCHEMBL29329312 | 0.78 | TSHR (0.40) | USP2TSHRCYP2D6CYP3A4CYP2C19 | |
| SCHEMBL25907682 | 0.75 | HSD11B1 (0.37) | USP2HSD11B1HDAC2HDAC1CYP2D6 | |
| SCHEMBL29329410 | 0.75 | USP2 (0.31) | USP2 | |
| SCHEMBL23589140 | 0.74 | HDAC2 (0.40) | USP2HSD11B1HDAC2HDAC1TSHR | |
| SCHEMBL25001376 | 0.73 | HSD11B1 (0.38) | HSD11B1HDAC2HDAC1TSHRCYP2D6 | |
| SCHEMBL18938451 | 0.72 | USP2 (0.32) | USP2TSHRCYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL24854091 | 0.72 | HSD11B1 (0.33) | HSD11B1HDAC2HDAC1CYP2D6DRD2 | |
| SCHEMBL24678300 | 0.72 | ALDH1A1 (0.38) | HSD11B1CYP2D6DRD2DRD3ALDH1A1 | |
| SCHEMBL19046977 | 0.72 | GRM5 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151346-A1 | HETEROARYL FLUOROALKENES AS DGK INHIBITORS | INCYTE CORPORATION (US) | 2024-07-18 | — | — | WO | disclosed |