Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 8/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330276 | 0.83 | MAPK11 (0.36) | MKNK1MKNK2CDK9CCNT1PNMT | |
| SCHEMBL30603347 | 0.82 | PTPN11 (0.38) | MKNK1MKNK2 | |
| SCHEMBL29329164 | 0.82 | PTPN11 (0.38) | MKNK1MKNK2 | |
| SCHEMBL29330192 | 0.72 | PTPN11 (0.38) | — | |
| SCHEMBL30603355 | 0.70 | DRD2 (0.36) | PNMT | |
| SCHEMBL29090285 | 0.70 | DRD2 (0.36) | PNMT | |
| SCHEMBL29329343 | 0.69 | TRPC5 (0.41) | — | |
| SCHEMBL21807225 | 0.67 | TRPC5 (0.55) | — | |
| SCHEMBL29090296 | 0.67 | KDR (0.41) | — | |
| SCHEMBL18910920 | 0.67 | DYRK1A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |