Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30603355 | 1.00 | DRD2 (0.36) | DRD2DRD3PNMTTRPV4KDR | |
| SCHEMBL29329164 | 0.85 | PTPN11 (0.38) | KDRHTR2CKCNH2 | |
| SCHEMBL30603347 | 0.85 | PTPN11 (0.38) | KDRHTR2CKCNH2 | |
| SCHEMBL30603333 | 0.75 | GPR119 (0.41) | — | |
| SCHEMBL30603337 | 0.75 | GPR119 (0.41) | — | |
| SCHEMBL29330276 | 0.73 | MAPK11 (0.36) | PNMTHTR2CKCNH2 | |
| SCHEMBL29090312 | 0.72 | TRPC5 (0.56) | ARKCNH2 | |
| SCHEMBL29329546 | 0.70 | MKNK1 (0.35) | PNMT | |
| SCHEMBL29330192 | 0.69 | PTPN11 (0.38) | HTR2C | |
| SCHEMBL21002977 | 0.66 | PNMT (0.34) | DRD2DRD3PNMTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731013-A | Heterocyclic compound, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-09-12 | — | — | CN | disclosed |