Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.46 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330248 | 0.90 | ESR1 (0.46) | TTBK1TTBK2ESR1CDK8PRKCQ | |
| SCHEMBL29330092 | 0.89 | ABL1 (0.41) | TTBK1TTBK2ESR1EGFRERBB2 | |
| SCHEMBL29330094 | 0.88 | PRKCQ (0.40) | TTBK1TTBK2ESR1CDK8PRKCQ | |
| SCHEMBL29328747 | 0.86 | EGFR (0.42) | TTBK1TTBK2ESR1EGFRERBB2 | |
| SCHEMBL29330567 | 0.86 | PRKCQ (0.45) | TTBK1TTBK2ESR1POLBPRKCQ | |
| SCHEMBL29329869 | 0.85 | ESR1 (0.42) | ESR1IDH1KIF11POLB | |
| SCHEMBL29328660 | 0.85 | SYK (0.39) | ESR1PRKCQBRAFKDR | |
| SCHEMBL29329538 | 0.85 | SYK (0.39) | ESR1CDK8EGFRPRKCQBRAF | |
| SCHEMBL29329432 | 0.85 | PRKCQ (0.38) | TTBK1TTBK2ESR1EGFRERBB2 | |
| SCHEMBL29329642 | 0.84 | ABL1 (0.46) | TTBK1TTBK2ESR1CTSSPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |