Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329368 | 0.92 | ESR1 (0.41) | ESR1SIRT2IDH1KIF11 | |
| SCHEMBL29330428 | 0.90 | ESR1 (0.42) | ESR1MAOB | |
| SCHEMBL29330430 | 0.87 | PRKCQ (0.43) | MAOBSIRT2SIRT1SIRT3MAPT | |
| SCHEMBL29329292 | 0.86 | SIRT2 (0.41) | MAOBSIRT2SIRT1SIRT3MAPT | |
| SCHEMBL29329720 | 0.85 | TTBK1 (0.46) | ESR1IDH1POLBKIF11 | |
| SCHEMBL29329944 | 0.85 | SIRT2 (0.41) | ESR1SIRT2SIRT1SIRT3 | |
| SCHEMBL29330342 | 0.84 | SYK (0.40) | ESR1SIRT2SIRT1SIRT3 | |
| SCHEMBL29330024 | 0.84 | MAOB (0.37) | ESR1MAOBSIRT2SIRT1SIRT3 | |
| SCHEMBL29330343 | 0.84 | CHRNA7 (0.41) | ESR1SIRT2SIRT1SIRT3 | |
| SCHEMBL29330433 | 0.84 | SYK (0.41) | ESR1MAOBMAOASIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |