Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 5/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329217 | 0.86 | TTBK1 (0.41) | PRKCQSYKRETESR1EGFR | |
| SCHEMBL29330163 | 0.84 | ESR1 (0.42) | PRKCQSYKESR1TTBK1TTBK2 | |
| SCHEMBL29330425 | 0.84 | ESR1 (0.42) | PRKCQSYKPRKCDRETESR1 | |
| SCHEMBL29329865 | 0.84 | PRKCQ (0.43) | PRKCQSYKPRKCDRETESR1 | |
| SCHEMBL29330164 | 0.84 | SYK (0.40) | PRKCQSYKSLC22A12ESR1APP | |
| SCHEMBL29329364 | 0.81 | KDR (0.39) | PRKCQSYKESR1CDK8CDK1 | |
| SCHEMBL29329431 | 0.81 | SYK (0.39) | PRKCQSYKPRKCDRETESR1 | |
| SCHEMBL29330093 | 0.81 | CHRNA7 (0.41) | PRKCQSYKESR1APP | |
| SCHEMBL29330161 | 0.81 | ESR1 (0.48) | PRKCQSYKPRKCDESR1EGFR | |
| SCHEMBL29330567 | 0.81 | PRKCQ (0.45) | PRKCQSYKPRKCDRETESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |