Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 11/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998246 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL21895486 | 0.73 | XIAP (0.42) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 | |
| SCHEMBL19153800 | 0.71 | PARP1 (0.50) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 | |
| SCHEMBL21808624 | 0.71 | PARP1 (0.46) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 | |
| SCHEMBL6837342 | 0.71 | PARP1 (0.46) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 | |
| SCHEMBL21339749 | 0.68 | SRC (0.52) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 | |
| SCHEMBL13853246 | 0.68 | PARP1 (0.50) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 | |
| SCHEMBL18237704 | 0.68 | PARP1 (0.42) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 | |
| SCHEMBL5841377 | 0.65 | ALDH1A1 (0.32) | ADORA2AALDH1A1DYRK1A | |
| SCHEMBL334691 | 0.64 | PARP1 (0.55) | SMN1; SMN2TSHRLMNAADORA2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-B1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |