Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.71 |
| ▸ | CA2 | P00918 | 13/20 | 0.71 |
| ▸ | CA12 | O43570 | 6/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 10/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL8657931 | 0.97 | CA1 (0.68) | CA1CA2CA12CA14TP53 | |
| SCHEMBL25129256 | 0.95 | CA2 (0.65) | CA1CA2CA12CA14TP53 | |
| SCHEMBL293342 | 0.95 | CA1 (0.81) | CA1CA2CA12CA14TP53 | |
| SCHEMBL293336 | 0.92 | CA2 (0.68) | CA1CA2CA12CA14TP53 | |
| SCHEMBL24248274 | 0.91 | CA1 (0.60) | CA1CA2CA12CA14TP53 | |
| SCHEMBL3790104 | 0.90 | CA2 (0.65) | CA1CA2CA12CA14TP53 | |
| SCHEMBL23319282 | 0.90 | CA2 (0.65) | CA1CA2CA12CA14TP53 | |
| SCHEMBL3793002 | 0.90 | CA2 (0.65) | CA1CA2CA12CA14TP53 | |
| SCHEMBL3795610 | 0.90 | CA2 (0.65) | CA1CA2CA12CA14TP53 | |
| SCHEMBL15546426 | 0.90 | CA2 (0.65) | CA1CA2CA12CA14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168181-B1 | MIXTURES FOR PRODUCING PHOTOACTIVE LAYERS FOR ORGANIC SOLAR CELLS AND ORGANIC PHOTODETECTORS | HELIATEK GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| US-20180346416-A1 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-12-06 | — | — | US | disclosed |
| US-10071957-B2 | N-substituted benzamides and methods of use thereof | GENENTECH, INC. (US) | 2018-09-11 | — | — | US | disclosed |
| EP-2870138-B1 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2018-08-22 | — | — | EP | disclosed |
| US-9831042-B2 | Organic dyes comprising a hydrazone moiety and their use in dye-sensitized solar cells | BASF SE (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20160126022-A1 | ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS | BASF SE (DE) | 2016-05-05 | — | — | US | disclosed |
| US-20150322002-A1 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2015-11-12 | — | — | US | disclosed |
| EP-2870138-A2 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2015-05-13 | — | — | EP | disclosed |
| EP-2870204-A2 | ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS | BASF SE (DE) | 2015-05-13 | — | — | EP | disclosed |
| WO-2014006544-A2 | ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS | BASF SE (DE) | 2014-01-09 | — | — | WO | disclosed |
| EP-0187521-A2 | Light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1986-07-16 | — | — | EP | disclosed |
| EP-0185506-A2 | Light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1986-06-25 | — | — | EP | disclosed |
| US-4595650-A | Magenta coupler of 5-pyrazolone type | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-17 | — | — | US | disclosed |
| EP-0182486-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-05-28 | — | — | EP | disclosed |
| EP-0178794-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0178165-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-04-16 | — | — | EP | disclosed |
| EP-0163314-A2 | Color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-12-04 | — | — | EP | disclosed |
| US-4515963-A | AMIDATIUON OF NAPHTHOLACTONE | CIBA GEIGY AG (CH) | 1985-05-07 | — | — | US | disclosed |
| EP-0133503-A2 | Color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-27 | — | — | EP | disclosed |
| EP-0084853-A1 | Process for the preparation of 1,8-naphtholactam compounds | CIBA-GEIGY AG (CH) | 1983-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322002-A1 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | BRIX1, SNRPD2, RDX | CA1 2618/4885CA2 2585/4885CA12 2163/4885 |
| US-10071957-B2 | N-substituted benzamides and methods of use thereof | BRIX1, SNRPD2, RDX | CA1 2618/4885CA2 2585/4885CA12 2163/4885 |
| US-20180346416-A1 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | BRIX1, RDX, P2RX3 | CA1 2544/4885CA2 1725/4885CA12 2356/4885 |
| US-20160126022-A1 | ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS | C1S, C9, C1R | CA1 294/4885CA2 174/4885CA12 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.