Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938633 | 0.87 | SIRT2 (0.35) | CHRNA7CHEK1SIRT2METPPARA | |
| SCHEMBL30938642 | 0.87 | SIRT2 (0.35) | CHRNA7CHEK1SIRT2METPPARA | |
| SCHEMBL29330952 | 0.87 | SIRT2 (0.35) | CHRNA7CHEK1SIRT2METPPARA | |
| SCHEMBL29331084 | 0.86 | SIRT2 (0.35) | CHEK1SIRT2METPPARAPPARD | |
| SCHEMBL29330716 | 0.86 | CHRNA7 (0.35) | CHRNA7CHEK1SIRT2PPARAPPARD | |
| SCHEMBL29333406 | 0.81 | SIRT2 (0.35) | CHRNA7SIRT2METPPARAPPARD | |
| SCHEMBL29330500 | 0.79 | P2RY14 (0.35) | CHRNA7KCNH2 | |
| SCHEMBL29330495 | 0.78 | IMPDH2 (0.38) | METPPARA | |
| SCHEMBL29329939 | 0.76 | APP (0.38) | CHRNA7METROCK2KCNH2 | |
| SCHEMBL29328811 | 0.76 | CDK2 (0.32) | CHEK1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |