Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 7/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22655285 | 0.86 | BMPR1B (0.44) | SRD5A1BRD4ALDH1A1GAABMPR1B | |
| SCHEMBL14780019 | 0.81 | SRD5A1 (0.46) | SRD5A1BRD4SRD5A2NPSR1CYP17A1 | |
| SCHEMBL14779919 | 0.81 | SRD5A1 (0.46) | SRD5A1BRD4ALDH1A1BMPR1BBMPR1A | |
| SCHEMBL8555796 | 0.79 | BRD4 (0.38) | SRD5A1BRD4BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL18497031 | 0.72 | POLB (0.52) | BRD4ALDH1A1GAAMAPTTP53 | |
| SCHEMBL8555101 | 0.71 | SRD5A1 (0.46) | SRD5A1BRD4ALDH1A1MAPTCYP17A1 | |
| SCHEMBL265640 | 0.70 | SRD5A1 (0.59) | SRD5A1BRD4CYP17A1CYP1A2CYP19A1 | |
| SCHEMBL8556027 | 0.70 | SRD5A1 (0.36) | SRD5A1BRD4SRD5A2CYP17A1CYP1A2 | |
| SCHEMBL29209108 | 0.70 | KMO (0.40) | BRD4MAPTTP53CYP1A2CYP11B1 | |
| SCHEMBL10646148 | 0.69 | SRD5A1 (0.36) | SRD5A1NPSR1MAPTTP53CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | SRD5A1 506/4885BRD4 3282/4885ALDH1A1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.