Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29332227 | 0.85 | POLB (0.50) | ALDH1A1POLBELANEMAPTMGLL | |
| SCHEMBL30969984 | 0.77 | LMNA (0.50) | POLBCYP1A2MAPK1 | |
| SCHEMBL29332053 | 0.76 | HSP90AA1 (0.43) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29332050 | 0.71 | POLB (0.47) | ALDH1A1POLBELANEMAPTALOX5 | |
| SCHEMBL29332052 | 0.70 | LMNA (0.46) | ALDH1A1ADRB1POLBMAPTMEN1 | |
| SCHEMBL29332051 | 0.70 | L3MBTL1 (0.53) | ALDH1A1ADRB1MAPTALOX5MGLL | |
| SCHEMBL29332228 | 0.70 | LMNA (0.54) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29331627 | 0.70 | KDM4E (0.42) | ALDH1A1ELANEMAPTMGLLMEN1 | |
| SCHEMBL29332141 | 0.67 | ELANE (0.47) | POLBELANEALOX5MGLLMEN1 | |
| SCHEMBL12469978 | 0.65 | OPRM1 (0.65) | ALDH1A1MAPTNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150252-A1 | PYRAZOLIDINE-3, 5-DIONE BASED COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2024-07-18 | — | — | WO | disclosed |