SCHEMBL29332777

Nc1nc2c(ncn2[C@H]2CC[C@@H](COP(=O)(S)O[C@H]3C[C@H](n4ccn5ccnc5c4=O)O[C@@H]3COP(=O)(O)S)O2)c(=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	1/20	0.48

▸	P2RY2	P41231	1/20	0.44

▸	P2RY4	P51582	1/20	0.44

▸	P2RY6	Q15077	1/20	0.44

▸	F2	P00734	2/20	0.42

▸	FUT5	Q11128	1/20	0.41

▸	NT5E	P21589	1/20	0.41

▸	P2RY1	P47900	1/20	0.41

▸	KRAS	P01116	2/20	0.40

▸	TGM2	P21980	1/20	0.39

▸	TERT	O14746	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16221825	0.91	POLB (0.56)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL29332814	0.87	POLB (0.47)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL20326935	0.86	POLB (0.51)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL22434567	0.86	POLB (0.51)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL16221597	0.86	POLB (0.51)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL18158912	0.85	POLB (0.50)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL16221824	0.85	POLB (0.50)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL16221826	0.85	F2 (0.55)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL23679650	0.85	POLB (0.48)	POLBP2RY2P2RY4P2RY6F2
SCHEMBL20327045	0.84	POLB (0.48)	POLBP2RY2P2RY4P2RY6F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3854799-B1	CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION	SHANGHAI DE NOVO PHARMATECH CO LTD (CN)	2024-07-17	—	—	EP	disclosed