Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333372 | 1.00 | ERN1 (0.38) | ERN1PTGDR2ALDH1A1L3MBTL1CYP2A6 | |
| SCHEMBL29333351 | 0.78 | POLB (0.47) | ERN1PTGDR2ALDH1A1CYP2A6POLB | |
| SCHEMBL17609337 | 0.74 | ERN1 (0.39) | ERN1PTGDR2ALDH1A1CYP2A6POLB | |
| SCHEMBL30178662 | 0.73 | ALDH1A1 (0.63) | ERN1PTGDR2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL11173 | 0.73 | ALDH1A1 (0.63) | ERN1PTGDR2ALDH1A1L3MBTL1PRKDC | |
| SCHEMBL29333369 | 0.73 | PTGDR2 (0.37) | PTGDR2ALDH1A1NPC1RAB9A | |
| SCHEMBL29333365 | 0.73 | PTGDR2 (0.37) | PTGDR2ALDH1A1NPC1RAB9A | |
| SCHEMBL29333360 | 0.71 | NR4A2 (0.41) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL29333364 | 0.71 | NR4A2 (0.41) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL27890878 | 0.71 | ERN1 (0.48) | ERN1PTGDR2ALDH1A1L3MBTL1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |