Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333369 | 1.00 | PTGDR2 (0.37) | PTGDR2MAPK1HSD17B10KDM4ETDP1 | |
| SCHEMBL29333349 | 0.78 | NPY1R (0.43) | PTGDR2SLC6A4 | |
| SCHEMBL4585924 | 0.74 | NPY1R (0.49) | PTGDR2KDM4ETDP1NPC1RAB9A | |
| SCHEMBL1427602 | 0.73 | PYCR1 (0.51) | PTGDR2MAPK1HSD17B10KDM4ETDP1 | |
| SCHEMBL30223764 | 0.73 | PYCR1 (0.51) | PTGDR2MAPK1HSD17B10KDM4ETDP1 | |
| SCHEMBL29333372 | 0.73 | ERN1 (0.38) | PTGDR2NPC1RAB9AALDH1A1 | |
| SCHEMBL29333375 | 0.73 | ERN1 (0.38) | PTGDR2NPC1RAB9AALDH1A1 | |
| SCHEMBL29333360 | 0.71 | NR4A2 (0.41) | HSD17B10KMT2AALDH1A1MAPT | |
| SCHEMBL29333364 | 0.71 | NR4A2 (0.41) | HSD17B10KMT2AALDH1A1MAPT | |
| SCHEMBL20564011 | 0.69 | PTGDR2 (0.41) | PTGDR2MAPK1HSD17B10NPC1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |