SCHEMBL29333889

SCHEMBL29333889

CC(C)(C)OC(=O)N1CCOC[C@H]1c1cc(Cl)cc(-c2ncnc(N)n2)c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MALT1 Q9UDY8 1/20 0.37
▸ PIK3CA P42336 17/20 0.37
▸ PIK3R1 P27986 15/20 0.37
▸ CCNC P24863 1/20 0.35
▸ CDK8 P49336 1/20 0.35
▸ AKT1 P31749 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30855074 1.00 MALT1 (0.37) MALT1PIK3CAPIK3R1CCNCCDK8
SCHEMBL29333891 0.91 MALT1 (0.37) MALT1PIK3CAPIK3R1CCNCCDK8
SCHEMBL29333887 0.88 MALT1 (0.39) MALT1PIK3CAPIK3R1CCNCCDK8
SCHEMBL29338457 0.85 CCNC (0.33) CCNCCDK8
SCHEMBL29333817 0.83 CCNC (0.34) PIK3CACCNCCDK8
SCHEMBL30855085 0.83 CCNC (0.36) PIK3CACCNCCDK8
SCHEMBL29333811 0.83 CCNC (0.36) PIK3CACCNCCDK8
SCHEMBL29333821 0.83 CCNC (0.36) PIK3CACCNCCDK8
SCHEMBL31008576 0.83 CCNC (0.34) PIK3CACCNCCDK8
SCHEMBL29333450 0.83 CCNC (0.34) PIK3CACCNCCDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 — — US disclosed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226114-A1 INHIBITORS AND USES THEREOF KEAP1, NQO1, NFE2L2 MALT1 4516/4885PIK3CA 3512/4885PIK3R1 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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