SCHEMBL2933392

SCHEMBL2933392

Cc1ccc(Pc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.53
LMNA P02545 2/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
TDP1 Q9NUW8 4/20 0.44
HPGD P15428 2/20 0.44
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
POLB P06746 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP2C19 P33261 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2154835 0.97 ACHE (0.50) ACHELMNATSHRALOX12TDP1
P-Xylene SCHEMBL7638602 0.97 ACHE (0.56) ACHELMNATSHRALOX12TDP1
P-Xylene SCHEMBL7641776 0.94 ACHE (0.53) ACHELMNATSHRALOX12TDP1
Toluene SCHEMBL9464383 0.92 ACHE (0.65) ACHELMNATSHRALOX12TDP1
SCHEMBL883788 0.88 ACHE (0.57) ACHELMNATSHRALOX12TDP1
Water SCHEMBL28646976 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
SCHEMBL29083662 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
SCHEMBL29126101 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
Hydrochloric Acid SCHEMBL2153693 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1
Fluoride SCHEMBL29226553 0.85 ACHE (0.53) ACHELMNATSHRALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507263-A1 EFFICIENT CATALYST FOR THE FORMATION OF POLYARYL HYDROCARBONS SUITABLE AS PRECURSORS FOR POLYDENTATE ORGANOPHOSPHORUS CATALYST LIGANDS Eastman Chemical Company (US) 2019-07-10 EP claimed
WO-2018044824-A1 EFFICIENT CATALYST FOR THE FORMATION OF POLYARYL HYDROCARBONS SUITABLE AS PRECURSORS FOR POLYDENTATE ORGANOPHOSPHORUS CATALYST LIGANDS EASTMAN CHEMICAL COMPANY (US) 2018-03-08 WO claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
CN-115746053-A Si-PCCP ligand, preparation method thereof, ethylene oligomerization catalyst and application thereof 万华化学集团股份有限公司 2023-03-07 CN disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
EP-1912953-B1 PROCESS FOR THE SYNTHESIS OF ROSUVASTATIN CALCIUM LEK PHARMACEUTICALS (SI) 2016-08-17 EP disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
US-8461248-B2 Resin composition and molded product thereof, and method for their production SONY CORPORATION (JP) 2013-06-11 US disclosed
US-8354530-B2 Preparation of HMG-CoA reductase inhibitors, in particular rosuvastatin calcium, introducing L-malic acid as source of chirality for side chain; statin core moiety is consecutively coupled with chiral segment containing 4 carbon atoms and segment containing 2 carbon atoms; treating hypercholesterolemia Lek Pharmaceuticals d. d (SI) 2013-01-15 US disclosed
EP-2230275-B1 Resin composition and molded product thereof, and method for their production SONY CORP (JP) 2012-11-21 EP disclosed
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed
CN-1216059-C Phosphonium salts, process for producing the same, use thereof, phosphine produced from the phosphonium salts and process for producing the same KURARAY CO (JP) 2005-08-24 CN disclosed
WO-2005040277-A1 FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY ALBEMARLE CORPORATION (US) 2005-05-06 WO disclosed
US-20050075024-A1 Flame retardant epoxy prepregs, laminates, and printed wiring boards of enhanced thermal stability ALBEMARLE CORPORATION 2005-04-07 US disclosed
US-6683136-B2 OF A NITRILE COPOLYMER RUBBER, USING A HYDROGENATION CATALYST, A COCATALYST, AND A PROTON ACCEPTOR THAT IS NON-COORDINATING WITH THE METAL COMPLEX CATALYST, SUCH AS EPOXIDIZED SOYBEAN OIL (ESBO) BAYER INC. (CA) 2004-01-27 US disclosed
CN-1384106-A Phosphonium salts, process for producing the same, use thereof, phosphine produced from the phosphonium salts and process for producing the same KURARAY CO (JP) 2002-12-11 CN disclosed
US-20020128393-A1 Esbo enhanced hydrogenation LANXESS INC. (CA) 2002-09-12 US disclosed
US-4293502-A CATALYST FOR OLIGOMERIZATION OF ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-10-06 US disclosed
US-3951661-A Silver halide emulsion containing an arylphosphonium salt as antifoggant KONISHIROKU PHOTO INDUSTRY CO. (JA) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization CCRL2, ARL1, OSBP2 ACHE 4524/4885LMNA 755/4885TSHR 2600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.