SCHEMBL29334289

SCHEMBL29334289

OC[C@@H]1COC[C@@H](c2cc(Cl)nc(-c3ccn4ccnc4c3)c2)N1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30855094 0.99 PIK3C3 (0.33) PIK3C3
SCHEMBL29337897 0.79
SCHEMBL29334281 0.77 TRPM5 (0.32)
SCHEMBL30855007 0.75 PIK3C3 (0.33) PIK3C3
SCHEMBL29333597 0.75 PIK3C3 (0.33) PIK3C3
SCHEMBL30855168 0.73 KCNK3 (0.37) PIK3C3
SCHEMBL29334284 0.73 KCNK3 (0.37) PIK3C3
SCHEMBL30855163 0.73 KCNK3 (0.37) PIK3C3
SCHEMBL29333568 0.70 KRAS (0.34) PIK3C3
SCHEMBL29337867 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226114-A1 INHIBITORS AND USES THEREOF KEAP1, NQO1, NFE2L2 PIK3C3 3551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.