SCHEMBL29334358

SCHEMBL29334358

N#Cc1ccc(S(=O)(=O)c2ccc(-n3c4ccccc4c4c5c(c6ccccc6n5-c5ccccc5)c5c(c6ccccc6n5-c5ccc(S(=O)(=O)c6ccc(C#N)cc6)cc5)c43)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP14 P54578 2/20 0.41
CTSG P08311 1/20 0.41
CMA1 P23946 1/20 0.41
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HTR6 P50406 3/20 0.36
SLC22A12 Q96S37 1/20 0.36
PDE10A Q9Y233 1/20 0.36
MAPK8 P45983 1/20 0.35
CYP19A1 P11511 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29333698 1.00 USP14 (0.41) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29334044 0.95 USP14 (0.41) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29335993 0.94 USP14 (0.39) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29334465 0.92 HTR6 (0.41) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29333704 0.91 KDM4E (0.36) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29334363 0.91 HSD11B1 (0.40) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29335461 0.91 KDM4E (0.40) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29334589 0.90 USP14 (0.41) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29334587 0.90 KDM4E (0.42) USP14CTSGCMA1KEAP1NFE2L2
SCHEMBL29334579 0.90 KDM4E (0.42) USP14CTSGCMA1KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151172-A1 CYANODIPHENYL SULFONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, AN EMISSIVE LAYER CONTAINING THEM, AN ELECTROLUMINESCENT DEVICE, AND THEIR USE Noctiluca S.A. (PL) 2024-07-18 WO disclosed